Statin Treatment in Diabetic Subjects: What the Heart Protection Study Shows
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چکیده
منابع مشابه
Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects
BACKGROUND Hyperglycemia-induced oxidative stress is one mechanism believed to underlie diabetic vascular disease. We tested the hypothesis that diabetic subjects heterozygous for extracellular superoxide dismutase (SOD3) R213G, which entails lower antioxidant capacity in tissues, have increased risk of cardiovascular disease and heart failure. METHODS We used the prospective Copenhagen Gener...
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چکیده ندارد.
15 صفحه اولNo impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study.
OBJECTIVES The aim of this study was to test the effects of the KIF6 Trp719Arg polymorphism (rs20455) on vascular risk and response to statin therapy in 18,348 participants from the Heart Protection Study. BACKGROUND There have been claims that noncarriers of the KIF6 719Arg variant receive little benefit from statin therapy. Screening for this genetic variant is now being used to influence s...
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ژورنال
عنوان ژورنال: Clinical Diabetes
سال: 2003
ISSN: 0891-8929,0891-8929
DOI: 10.2337/diaclin.21.4.151